Nuclear expression of the RNA-binding protein RBM3 is associated with an improved clinical outcome in breast cancer
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چکیده
منابع مشابه
High RNA-Binding Motif Protein 3 (RBM3) Expression is Independently Associated with Prolonged Overall Survival in Intestinal-Type Gastric Cancer
BACKGROUND High expression of the RNA-binding motif protein 3 (RBM3) has previously been described as a favorable clinicopathological factor in several cancers, including ovarian cancer, colorectal cancer, prostate cancer, and breast cancer. The aim of this study was to examine the prognostic implications of RBM3 expression in gastric cancer. MATERIAL AND METHODS Immunohistochemical analysis of...
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چکیده: سرطان پستان دومین عامل مرگ مرتبط با سرطان در خانم ها است. از آنجا که سرطان پستان یک تومور وابسته به هورمون است، می تواند توسط وضعیت هورمون های استروئیدی شامل استروژن و پروژسترون تنظیم شود. استروژن نقش مهمی در توسعه و پیشرفت سرطان پستان ایفا می کند و تاثیر خود را روی بیان ژن های هدف از طریق گیرنده های استروژن اعمال می کند. اما گروه دیگری از گیرنده های هسته ای به نام گیرنده های مرتبط به ا...
15 صفحه اولEvaluating the clinical importance of long-non coding RNA MALAT1 expression in breast cancer
Background: Breast cancer is one of the major causes of illness and mortality among women. Long non-coding RNAs (LncRNAs) have important role in tumor development and progression. Metastasis-associated lung adenocarcinoma transcript 1 (MALAT1) is a lncRNA that deregulates in several cancers, however, its value in the diagnosis of breast cancer is unclear. This study was conducted to investigate...
متن کاملHigh RBM3 expression is associated with an improved survival and oxaliplatin response in patients with metastatic colorectal cancer
BACKGROUND High expression of the RNA-binding motif protein 3 (RBM3) has been shown to correlate, with prolonged survival in several malignant diseases and with the benefit of platinum-based chemotherapy in ovarian cancer. The aim of this study was to evaluate RBM3 in metastatic colorectal cancer (mCRC) as a prognostic factor for overall survival and in relation to benefit of first-line chemoth...
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ژورنال
عنوان ژورنال: Modern Pathology
سال: 2009
ISSN: 0893-3952,1530-0285
DOI: 10.1038/modpathol.2009.124